Glixx Laboratories Inc
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Glixx Laboratorie
CAS: 1446311-56-3
Chemical Name: (S)-3-(6,8-Dimethylimidazo[1,2-a]pyrazin-2-yl)-7-(4-ethyl-3-methylpiperazin-1-yl)-2H-chromen-2-one
Purity: >98% (HPLC)
Novel selective RNA-binding ligand, acting by binding SMN2 pre-mRNA and thereby increasing the affinity of the RNA binding proteins far upstream element binding protein 1 (FUBP1) and KH-type splicing regulatory protein (KHSRP) to the SMN2 pre-mRNA complex
References:
1) https://science.sciencemag.org/content/345/6197/688/tab-figures-data
2) https://www.pnas.org/content/115/20/E4604
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