Glixx Laboratories Inc

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Glixx Laboratorie

 

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OT-82

 

CAS: 1800487-55-1

 

Chemical Name: N-(3-(1H-Pyrazol-4-yl)propyl)-3-((4-fluorophenyl)ethynyl)-4-(pyridin-4-yl)benzamide

 

 
GLXC-22045For Lab R&D Uses Only
        Cat No: GLXC-22045

 

Purity:               >98% (HPLC)

Storage:             Refrigerator (4 °C)

 

 

Product Description:

Novel nicotinamide phosphoribosyltransferase (NAMPT) inhibitor, exerting its antileukemic action by depleting NAD+ and ATP, inhibiting the NAD+-requiring DNA damage repair enzyme PARP-1, increasing mitochondrial ROS levels and inducing DNA damage, culminating in apoptosis induction

 

Ref: https://www.nature.com/articles/s41375-019-0692-5

 

Analytical data click for PDF file

 

 

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