Glixx Laboratories Inc
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Glixx Laboratorie
CAS: 2141978-86-9
Chemical Name: ZIKV inhibitor K22; anti-HCoV-229E K22; (Z)-N-[3-[4-(4-Bromophenyl)-4-hydroxypiperidin-1-yl]-3-oxo-1-phenylprop-1-en-2-yl]benzamide
Purity: >98% (HPLC)
Potent antiviral agent against a broad range of coronaviruses by targeting membrane-bound viral RNA replication, effectively inhibiting ZIKV with IC50 of 2.1 μM, also inhibiting HCoV-229E during the early, post entry phase of the viral life cycle
References:
1) https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6201103/
2) https://journals.plos.org/plospathogens/article?id=10.1371/journal.ppat.1004166
3) https://www.sciencedirect.com/science/article/pii/S0168170217308560
4) https://onlinelibrary.wiley.com/doi/full/10.1002/ardp.201800330
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