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CAS: N/A
Chemical Name: (3R,5R)-7-(3-(3-(3-(1-(14-((2-(2,6-Dioxopiperidin-3-yl)-1,3-dioxoisoindolin-4-yl)amino)-3,6,9,12-tetraoxatetradecyl)-1H-1,2,3-triazol-4-yl)propoxy)phenyl)-2-(4-fluorophenyl)-5-isopropyl-4-(phenylcarbamoyl)-1H-pyrrol-1-yl)-3,5-dihydroxyheptanoic acid
Purity: >98% (HPLC)
Novel degrader of HMGCR protein, potently blocking cholesterol biosynthesis with less compensatory upregulation of HMGCR
Ref: https://pubs.acs.org/doi/10.1021/acs.jmedchem.0c00339
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