Glixx Laboratories Inc
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Glixx Laboratorie
CAS: 1903763-82-5
Chemical Name: PF-07923568; RV521; RV-521; 1'-[[5-(Aminomethyl)-1-(4,4,4-trifluorobutyl)benzimidazol-2-yl]methyl]-6'-fluorospiro[cyclopropane-1,3'-indole]-2'-one
Purity: >98% (HPLC)
Novel orally bioavailable inhibitor of respiratory syncytial virus (RSV) fusion, exhibiting a mean IC50 of 1.2 nM against a panel of RSV A and B laboratory strains and clinical isolates with antiviral efficacy in the Balb/C mouse model of RSV infection
References:
1) https://pubs.acs.org/doi/10.1021/acs.jmedchem.0c01882
2) https://aac.asm.org/content/64/2/e01884-19.long
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