Glixx Laboratories Inc
Your exclusive source for bioactive molecules
Glixx Laboratorie
CAS: 2470908-79-1
Chemical Name: 4-(3-((4-(1-(2-Bromobenzyl)-2-phenyl-1H-indol-3-yl)-7-methoxyquinazolin-6-yl)oxy)propyl)morpholine
Purity: >98% (HPLC)
Novel highly effective and orally active P-gp inhibitor, effectively reversing multidrug resistance (MDR) to paclitaxel and colchicine in SW620/AD300 and HEK293T-ABCB1 cells, stimulating the P-gp ATPase activity and having moderate inhibition against CYP3A4
Ref: https://pubs.acs.org/doi/10.1021/acs.jmedchem.1c01452
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