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CAS: N/A
Chemical Name: 4-(2-(5-Amino-2-(furan-2-yl)-7H-pyrazolo[4,3-e][1,2,4]triazolo[1,5-c]pyrimidin-7-yl)ethyl)-N-(2-aminophenyl)benzamide
Purity: >98% (HPLC)
Novel dual A2AR antagonist and histone deacetylase (HDAC) inhibitor, exhibiting potent binding to A2AR (Ki = 2.2 nM) and selective inhibition of HDAC1 (IC50 = 80.2 nM), with good antiproliferative activity against tumor cell lines in vitro
Ref: https://pubs.acs.org/doi/10.1021/acs.jmedchem.1c01155
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