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CAS: N/A
Chemical Name: 1-[3-[4-(2-Chlorophenyl)-5-pyrimidin-4-yl-1,2,4-triazol-3-yl]cyclobutyl]-2-oxo-3H-benzimidazole-5-carbonitrile
Purity: >98% (HPLC)
Novel potent tankyrase inhibitor, displays high target affinity on tankyrase 1 and 2 with biochemical and cellular IC50 values of 29 nM, 6.3 nM and 19 nM, respectively, and high selectivity toward other poly (ADP-ribose) polymerase enzymes
Ref: https://pubs.acs.org/doi/10.1021/acs.jmedchem.7b00883
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