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CAS: N/A
Chemical Name: 5-Fluoro-2,4-bis(prop-2-yn-1-yloxy)pyrimidine
Purity: >95% (HPLC)
Novel palladium-activated 5-FU prodrug, being completely innocuous to cells and highly resistant to metabolization by primary hepatocytes and liver S9 fractions (the main metabolic route for 5-FU degradation), and rapidly converted into 5-FU in the presence of a palladium (Pd) source
Ref: https://pubs.acs.org/doi/10.1021/acs.jmedchem.1c01733
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