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FGFR4 inhibitor 7v

 

CAS: N/A

 

Chemical Name: (R)-N-(2-((5-(1-(3,5-Dichloropyridin-4-yl)ethoxy)-1H-indazol-3-yl)amino)-3-fluoro-5-(4-morpholinopiperidin-1-yl)phenyl)acrylamide

 

 
GLXC-25448For Lab R&D Uses Only
        Cat No: GLXC-25448

 

Purity:               >98% (HPLC)

Storage:             Refrigerator (4 °C)

 

 

Product Description:

Novel highly selective covalent inhibitor of wild-type and gatekeeper mutant FGFR4, exhibiting excellent potency against FGFR4, FGFR4V550L, and FGFR4V550M with nanomolar activity in both the biochemical and cellular assays while sparing FGFR1/2/3

 

Ref: https://pubs.acs.org/doi/10.1021/acs.jmedchem.2c00096

 

Analytical data click for PDF file

 

 

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