Glixx Laboratories Inc

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Glixx Laboratorie

 

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JDQ443

 

CAS: 2653994-08-0

 

Chemical Name: Opnurasib; NVP-JDQ443; 1-[6-[4-(5-Chloro-6-methyl-1H-indazol-4-yl)-5-methyl-3-(1-methylindazol-5-yl)pyrazol-1-yl]-2-azaspiro[3.3]heptan-2-yl]prop-2-en-1-one

 

 
GLXC-25533For Lab R&D Uses Only
        Cat No: GLXC-25533

 

Purity:               >98% (HPLC)

Storage:             Refrigerator (4 °C)

 

 

Product Description:

Novel covalent KRASG12C inhibitor, binding under the switch II loop with a novel binding mode, exploiting unique interactions with the KRASG12C protein compared to sotorasib and adagrasib

 

Ref: https://aacrjournals.org/mct/article/20/12_Supplement/P124/676115/Abstract-P124-JDQ443-a-covalent-irreversible

 

Analytical data click for PDF file

 

 

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