Glixx Laboratories Inc

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YL93

 

CAS: 2771313-42-7

 

Chemical Name: 4-((2R,3S,4S,5S)-3-(3-Chloro-2-fluorophenyl)-4-(4-chloro-2-fluorophenyl)-5-neopentyl-4-(((pyridin-4-ylmethyl)amino)methyl)pyrrolidine-2-carboxamido)-3-methoxybenzoic acid

 

 
GLXC-25581For Lab R&D Uses Only
        Cat No: GLXC-25581

 

Purity:               >98% (HPLC)

Storage:             Refrigerator (4 °C)

 

 

Product Description:

Novel MDM2/4 dual inhibitor with Ki values of 1.1 and 642 nM, respectively, increasing cellular protein levels of p53 and p21 and upregulating the expression of p53-targeted genes in RKO cells with MDM4 amplification, inducing cell-cycle arrest and apoptosis

 

Ref: https://pubs.acs.org/doi/10.1021/acs.jmedchem.2c00095

 

Analytical data click for PDF file

 

 

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