Glixx Laboratories Inc
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Glixx Laboratorie
CAS: N/A
Chemical Name: (R)-4,6-Dimethoxy-3-(4-methoxyphenyl)-2,3-dihydro-1H-inden-1-one
Purity: >98% (HPLC)
First-in-class TAK1-MKK3 protein-protein interaction (PPI) inhibitor for the treatment of ulcerative colitis through modulating TNF-α production, suppressing the TAK1/MKK3/p38/MnK1/MK2/elF4E signal pathways through binding with MKK3 and disrupting the TAK1 phosphorylating MKK3
Ref: https://pubs.acs.org/doi/10.1021/acs.jmedchem.1c02198
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