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CAS: N/A
Chemical Name: N-((R)-5-(4-(4-(Bis(2-chloroethyl)amino)phenyl)butanamido)-6-oxo-6-((2-(5-((3aR,4R,6aS)-2-oxohexahydro-1H-thieno[3,4-d]imidazol-4-yl)pentanamido)ethyl)amino)hexyl)-3-((4-(methylamino)quinazolin-2-yl)amino)benzamide
Purity: >98% (HPLC)
Novel covalent cross-linker to the SARS-CoV-2 frameshifting element (FSE), directly targeting engagement of the SARS-CoV-2 FSE in cells, dose dependently reducing frameshifting in cells expressing the SARS-CoV-2 FSE, with no significant effect on frameshifting for the SARS-CoV construct
Ref: https://pubs.acs.org/doi/10.1021/acscentsci.0c00984?fig=fig1&ref=pdf
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