Glixx Laboratories Inc
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Glixx Laboratorie
CAS: 1184987-29-8
Chemical Name: 2-[(4-Fluorophenyl)sulfonylamino]-N-(2-methyl-5-thiomorpholin-4-ylsulfonylthiophen-3-yl)acetamide
Purity: >98% (HPLC)
Novel potent SHIP1 selective agonist, being independent of the C2 domain and increasing PI(3,4)P2 levels, reducing IL-6, TNF-α, and iNOS induction in microglia and macrophages, promoting phagocytic degradation of lipid-laden but not protein cargo in microglia
Ref: https://www.cell.com/iscience/fulltext/S2589-0042(22)00440-0
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