Glixx Laboratories Inc

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VIR251

 

CAS: N/A

 

Chemical Name: Methyl (4S,7S,E)-7-(aminomethyl)-4-(4-hydroxyphenethyl)-2,5,8,11-tetraoxo-3,6,9,12-tetraazahexadec-14-en-16-oate

 

 
GLXC-25820For Lab R&D Uses Only
        Cat No: GLXC-25820

 

Purity:               >98% (HPLC)

Storage:             Refrigerator (4 °C)

 

 

Product Description:

Novel covalent inhibitor of the SARS-CoV-2 papain-like protease (PLpro), irreversibly inactivate PLpro by forming a covalent bond with a specific residue of the catalytic site (Cys111), through a Michael addition reaction

 

References:

1) https://www.mdpi.com/1422-0067/23/10/5855

2) https://pubs.acs.org/doi/10.1021/acs.jpcb.1c07060

3) https://www.biorxiv.org/content/10.1101/2020.04.29.068890v2

 

Analytical data click for PDF file

 

 

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