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(S)-Sunvozertinib

 

CAS: 2370013-49-1

 

Chemical Name: (S)-DZD9008; N-[5-[[4-[5-Chloro-4-fluoro-2-(2-hydroxypropan-2-yl)anilino]pyrimidin-2-yl]amino]-2-[(3S)-3-(dimethylamino)pyrrolidin-1-yl]-4-methoxyphenyl]prop-2-enamide

 

 
GLXC-25828For Lab R&D Uses Only
        Cat No: GLXC-25828

 

Purity:               >98% (HPLC)

Storage:             Refrigerator (4 °C)

 

 

Product Description:

The S-enantiomer of Sunvozertinib, showing 51.2 nM, 51.9 nM, 1 nM, and 21.2 nM against EGFR exon 20 NPH and ASV insertions, EGFR L858R/T790M mutation and Her2 exon20 YVMA insertion, respectively, also inhibiting BTK

 

References:

1) https://www.tandfonline.com/doi/abs/10.1080/03007995.2022.2083326

2) https://aacrjournals.org/cancerdiscovery/article/doi/10.1158/2159-8290.CD-21-1615/694369/Sunvozertinib-a-selective-EGFR-inhibitor-for

 

Analytical data click for PDF file

 

 

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