Glixx Laboratories Inc
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Glixx Laboratorie
CAS: 2210228-45-6
Chemical Name: 4'-(N-(1-(Cyclopropanecarbonyl)-1,2,3,4-tetrahydroquinolin-7-yl)sulfamoyl)-[1,1'-biphenyl]-3-carboxamide
Purity: >98% (HPLC)
Novel inhibitor of the DNA repair enzyme 8-oxoguanine DNA glycosylase 1 (OGG1), mitigating bacterial infection via an mtDNA-mediated cGAS pathway and attenuating lung injury caused by PA14 infection in vivo
References:
1) https://www.sciencedirect.com/science/article/pii/S2213231720310533
2) https://www.jimmunol.org/content/205/8/2231.long
3) https://pubs.acs.org/doi/10.1021/jacs.7b09316
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