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Nirogacestat

 

CAS: 1290543-63-3

 

Chemical Name: PF-03084014; (2S)-2-[[(2S)-6,8-Difluoro-1,2,3,4-tetrahydro-2-naphthalenyl]amino]-N-[1-[2-[(2,2-dimethylpropyl)amino]-1,1-dimethylethyl]-1H-imidazol-4-yl]-pentanamide; PF-03084014; Nirogacestat

 

GLXC-02736   Cat №: GLXC-02736

 


Purity:               >98% (HPLC)

Storage:             +4°C

 


Product Description:

Novel γ-secretase inhibitor that reduces amyloid-β (Aβ) production with an in vitro IC50 of 1.2 nM (whole-cell assay) to 6.2 nM (cell-free assay).

 

References:

https://pubmed.ncbi.nlm.nih.gov/?term=Nirogacestat&sort=date

 

NMR data click for PDF file

HPLC data click for PDF file


 

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