For Lab R&D Uses Only

Purity:               >98% (HPLC)

Product Description:

Novel multitargeting HDAC inhibitor, effectively inducing the apoptosis of cancer cells and suppressing the tumor by strongly inhibiting the RAS-RAF-MEK-ERK signaling pathway and the acetylation level of HDAC3, not only showing stronger antiproliferative activity against many types of cancer cells including solid tumor cells but also presenting stronger antitumor activity than oxaliplatin, SAHA, and rigosertib in the HT-29 xenograft mouse models without significant systemic toxicity

Reference:

https://pubs.acs.org/doi/10.1021/acs.jmedchem.3c01941

Analytical data

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