Glixx Laboratories Inc
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Glixx Laboratorie
CAS: 3032642-29-5
Chemical Name: EGFRL858R/T790M/ACK1-IN-21a; N-(3-((6-Chloro-2-((1-ethyl-1H-pyrazol-4-yl)amino)quinazolin-4-yl)amino)phenyl)acrylamide
For Lab R&D Uses Only
Purity: >98% (HPLC)
Novel potent dual EGFRL858R/T790M/ACK1 inhibitor with IC50s at 23 nM and 263 nM, respectively, showing significant antitumor effects and good safety in ADZR xenograft-bearing mice
Reference:
https://pubs.acs.org/doi/10.1021/acs.jmedchem.3c01934
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