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CAS: 3018085-89-4
Chemical Name: 5-((1-(3-Carboxy-4-((1-(4-fluorophenyl)-1H-pyrazole)-4-sulfonamido)benzyl)azetidin-3-yl)oxy)-2-((1-(4-fluorophenyl)-1H-pyrazole)-4-sulfonamido)benzoic acid
For Lab R&D Uses Only
Purity: >98% (HPLC)
Novel inhibitor of the lipooligosaccharide transporter MsbA, exhibiting antibacterial activity in the presence of human serum and a pharmacokinetic profile sufficient to achieve efficacy against A. baumannii in murine septicemia and lung infection models
Reference:
https://pubs.acs.org/doi/10.1021/acs.jmedchem.4c01277
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