Glixx Laboratories Inc

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Glixx Laboratorie

 

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SMIP-031

 

CAS: N/A

 

Chemical Name: 8-Ethoxy-2-fluoro-5-(2-hydroxyethyl)phenanthridin-5-ium bromide

 

 
GLXC-28720For Lab R&D Uses Only
        Cat No: GLXC-28720

 

Purity:               >98% (HPLC)

Storage:             Refrigerator (4 °C)

 

 

Product Description:

Novel potent inhibitor for PPM1A (IC50 = 180 nM), efficiently increasing the level of phosphorylation of S403-p62 and the expression of LC3B-II to activate autophagy, resulting in the dose-dependent clearance of Mtb in infected macrophages

 

Reference:

https://pubs.acs.org/doi/10.1021/acs.jmedchem.4c00513

 

Analytical data click for PDF file

 

 

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