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CAS: N/A
Chemical Name: 8-Ethoxy-2-fluoro-5-(2-hydroxyethyl)phenanthridin-5-ium bromide
For Lab R&D Uses Only
Purity: >98% (HPLC)
Novel potent inhibitor for PPM1A (IC50 = 180 nM), efficiently increasing the level of phosphorylation of S403-p62 and the expression of LC3B-II to activate autophagy, resulting in the dose-dependent clearance of Mtb in infected macrophages
Reference:
https://pubs.acs.org/doi/10.1021/acs.jmedchem.4c00513
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