Glixx Laboratories Inc
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Glixx Laboratorie
CAS: 1416435-96-5
Chemical Name: GTPL6658; 5-Isoxazoyl-Cha-Ile-spiroindene-1,4-piperidine; N-[(2S)-3-Cyclohexyl-1-[[(2S,3R)-3-methyl-1-oxo-1-spiro[indene-1,4'-piperidine]-1'-ylpentan-2-yl]amino]-1-oxopropan-2-yl]-1,2-oxazole-5-carboxamide
For Lab R&D Uses Only
Purity: >98% (HPLC)
Biased antagonist of PAR2, selectively inhibiting PAR2/Gq/11/Ca2+/PKC signalling, leading to anti-inflammatory activity in vivo, while being an agonist in activating three other PAR2-activated pathways (cAMP, ERK, Rho) in human cells
References:
https://pubmed.ncbi.nlm.nih.gov/?term=GB88&sort=date
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