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CAS: 2560576-15-8
Chemical Name: 5-(Difluoromethyl)-3-((1-((5-fluoro-2-oxo-1,2-dihydropyridin-3-yl)methyl)-6-oxo-4-(1,1,2,2-tetrafluoroethyl)-1,6-dihydropyrimidin-5-yl)oxy)-2-methylbenzonitrile
Purity: >98% (HPLC)
Novel potent targeted activator of cell kill (TACK) agent, binding the reverse transcriptase-p66 domain of monomeric Gag-Pol and acting as an allosteric modulator to accelerate dimerization, resulting in HIV-1+ cell death through premature intracellular viral protease activation
Reference:
https://www.science.org/doi/10.1126/scitranslmed.abn2038
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