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CAS: 1370448-25-1

 

Chemical Name: Clesacostat; 4-(4-(1-Isopropyl-7-oxo-1,4,6,7-tetrahydrospiro[indazole-5,4'-piperidine]-1'-carbonyl)-6-methoxypyridin-2-yl)benzoic acid

 

 
GLXC-22850For Lab R&D Uses Only
        Cat No: GLXC-22850

 

Purity:               >98% (HPLC)

Storage:             Refrigerator (4 °C)

 

 

Product Description:

Novel potent, orally bioavailable, dual acetyl-CoA carboxylase (ACC1/ACC2) inhibitor, also being a substrate of the organic anion transporting polypeptides, leading to asymmetrical tissue distribution and increased concentrations in the liver relative to plasma and other tissues

 

References:

1) https://pubs.acs.org/doi/10.1021/acs.jmedchem.0c00640

2) https://www.cmghjournal.org/article/S2352-345X(20)30090-4/fulltext

3) https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7317421/

 

Analytical data click for PDF file

 

 

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