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Glixx Laboratorie
CAS: 2109805-80-1
Chemical Name: (2R,3S,4R)-3-(2'-Fluoro-[1,1'-biphenyl]-4-yl)-4-(hydroxymethyl)azetidine-2-carbonitrile
Cat No: GLXC-10482
For Lab R&D Uses Only
Purity: >98% (HPLC)
Storage: Refrigerator (4 °C)
Novel allosteric inhibitor of Mycobacterium tuberculosis tryptophan synthase (TrpAB), bindomg at the TrpAB α-β-subunit interface and affecting multiple steps in the enzyme's overall reaction, resulting in inhibition not easily overcome by changes in metabolic environment.
Ref: https://www.nature.com/articles/nchembio.2420
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