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Glixx Laboratorie
CAS: N/A
Chemical Name: MDM2/X peptide dual inhibitor; LTFEHYWAQLTS; Leu-Thr-Phe-Glu-His-Tyr-Trp-Ala-Gln-Leu-Thr-Ser
Purity: >98% (HPLC)
Potent Peptide dual inhibitor of MDM2/X, inhibiting p53 interactions with MDM2 (IC50 = 10 nmol/L) and MDMX (IC50 = 100 nmol/L), inducing apoptosis and cell cycle arrest of cell lines with overexpressed MDM2/X
Ref: https://cancerres.aacrjournals.org/content/67/18/8810.full
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