Glixx Laboratories Inc
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Glixx Laboratorie
CAS: 1848959-10-3
Chemical Name: 4-Amino-7-[(2R,3R,4S,5R)-3,4-dihydroxy-5-[(sulfamoylamino)methyl]oxolan-2-yl]-5-[2-(2-ethoxy-6-fluorophenyl)ethynyl]pyrrolo[2,3-d]pyrimidine
Purity: >98% (HPLC)
Novel NEDD8-activating enzyme inhibitor, activating both intrinsic and extrinsic apoptotic pathways via c-Myc-mediated regulation in acute myeloid leukemia
References:
1) https://www.nature.com/articles/s41388-020-01586-4
2) https://onlinelibrary.wiley.com/doi/full/10.1111/cas.14209
3) https://mct.aacrjournals.org/content/18/7/1205.long
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