Glixx Laboratories Inc

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Glixx Laboratorie

 

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JH-RE-06

 

CAS: 1361227-90-8

 

Chemical Name: 8-Chloro-2-[(2,4-dichlorophenyl)amino]-3-(3-methylbutanoyl)-5-nitro-4(1H)-quinolinone

 

 
GLXC-21219For Lab R&D Uses Only
        Cat No: GLXC-21219

 

Purity:               >98% (HPLC)

Storage:             Refrigerator (4 °C)

 

 

Product Description:

Novel inhibitor of mutagenic translesion synthesis (TLS), disrupting mutagenic TLS by preventing recruitment of mutagenic POL ζ, targets a nearly featureless surface of REV1 that interacts with the REV7 subunit of POL ζ, inducing REV1 dimerization to block the REV1-REV7 interaction

 

Reference:

https://www.cell.com/cell/pdf/S0092-8674(19)30556-2.pdf

 

 

Analytical data click for PDF file

 

 

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