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Glixx Laboratorie
CAS: 2787482-24-8
Chemical Name: Methyl N6-(bicyclo[2.2.1]heptan-2-yl)-N2-((S)-2-((S)-2-((S)-2-(4-(tert-butyl)benzamido)-3-phenylpropanamido)-2-cyclobutylacetamido)-5-morpholinopentanoyl)-N6-isobutyl-L-lysyl-L-serinate
Purity: >98% (HPLC)
Novel potent and selective PAM of CBX8, blocking H3K27me3 binding and enhancing CBX8 affinity for nucleic acids, evicting PRC1 from H3K27me3 targets triggering DLBCL cell differentiation
Ref: https://www.cell.com/cell-chemical-biology/fulltext/S2451-9456(21)00437-2
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