Glixx Laboratories Inc
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Glixx Laboratorie
CAS: 1210608-43-7
Chemical Name: PIM447; N-(4-((1R,3S,5S)-3-Amino-5-methylcyclohexyl)pyridin-3-yl)-6-(2,6-difluorophenyl)-5-fluoropicolinamide
Cat No: GLXC-10644
For Lab R&D Uses Only
Purity: >98% (HPLC)
Storage: Refrigerator (4 °C)
Potent and specific pan-PIM inhibitor, inhibiting proliferation of several AML cell lines, showing dual antitumoral and bone antiresorptive effects
References:
1) https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6862308/
2) https://www.nature.com/articles/s41375-019-0482-0
3) https://pubs.acs.org/doi/10.1021/acs.jmedchem.5b01275
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