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CAS: 1210416-52-6 (2 HCl: 1820565-69-2)
Chemical Name: PIM-447 HCl; N-[4-[(1R,3S,5S)-3-amino-5-methylcyclohexyl]pyridin-3-yl]-6-(2,6-difluorophenyl)-5-fluoropyridine-2-carboxamide hydrochloride
Cat No: GLXC-10780
Purity: >98% (HPLC)
Storage: Refrigerator (4 °C)
Potent and specific pan-PIM inhibitor, inhibiting proliferation of several AML cell lines, showing dual antitumoral and bone antiresorptive effects
References:
1) https://onlinelibrary.wiley.com/doi/full/10.1111/bjh.15033
2) https://www.oncotarget.com/article/11457/text/
3) https://clincancerres.aacrjournals.org/content/23/1/225.long
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