Glixx Laboratories Inc
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Glixx Laboratorie
CAS: 1542132-88-6
Chemical Name: Methyl (S,E)-7-((1-(2-(((diethylamino)methyl)amino)-2-oxoethyl)-2-oxo-1,2-dihydropyridin-3-yl)amino)-6-(1-methyl-1H-imidazole-5-carboxamido)-7-oxohept-2-enoate
Purity: >98% (HPLC)
The First-In-Class tissue transglutaminase inhibitor for the treatment of celiac disease, selectively binding to the active state of TG2 and forming a stable covalent bond with the cysteine in its catalytic center
References:
1) https://www.mdpi.com/2073-4409/11/10/1667
2) https://www.nejm.org/doi/10.1056/NEJMoa2032441
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