Glixx Laboratories Inc

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Glixx Laboratorie

 

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INY-03-041

 

CAS: N/A

 

Chemical Name: 3-(4-(10-(((S)-2-(4-Chlorophenyl)-3-(4-((5R,7R)-7-hydroxy-5-methyl-6,7-dihydro-5H-cyclopenta[d]pyrimidin-4-yl)piperazin-1-yl)-3-oxopropyl)amino)decyl)-1-oxoisoindolin-2-yl)piperidine-2,6-dione

 

 
GLXC-22005For Lab R&D Uses Only
        Cat No: GLXC-22005

 

Purity:               >98% (HPLC)

Storage:             Refrigerator (4 °C)

 

 

Product Description:

Novel selective pan-AKT degrader, inducing potent degradation of all three AKT isoforms and displaying enhanced anti-proliferative effects relative to GDC-0068, promoting sustained AKT degradation and inhibition of downstream signaling effects for up to 96 h

 

Refernces:

1) https://www.sciencedirect.com/science/article/abs/pii/S2451945619303964

2) https://www.biorxiv.org/content/10.1101/848887v1.full

 

Analytical data click for PDF file

 

 

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