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CAS: N/A

 

Chemical Name: 4-((9-Chloro-7-(2-fluoro-6-methoxyphenyl)-5H-benzo[c]pyrimido[4,5-e]azepin-2-yl)methyl)-N-(5-((5-(4-(2,4-dioxotetrahydropyrimidin-1(2H)-yl)phenoxy)pentyl)oxy)pentyl)-2-methoxybenzamide

 

 
GLXC-90356For Lab R&D Uses Only
        Cat No: GLXC-90356

 

Purity:               >98% (HPLC)

Storage:             Refrigerator (4 °C)

 

 

Product Description:

Second-generation alisertib-derived Aurora A PROTAC, exhibiting superior activity as a degrader in the HiBiT assay, Western blot analysis, and proteomics profiling compared to JB170

 

Reference:

https://pubs.acs.org/doi/10.1021/acs.jmedchem.5c03024

 

Analytical data click for PDF file

 

 

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