Glixx Laboratories Inc

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KS-19

 

CAS: N/A

 

Chemical Name: (4-(6-Chloro-7-(5-chloro-2-methoxyphenyl)-8-fluoroquinazolin-4-yl)piperazin-1-yl)(5-nitrofuran-2-yl)methanone

 

 
GLXC-26312For Lab R&D Uses Only
        Cat No: GLXC-26312

 

Purity:               >98% (HPLC)

Storage:             Refrigerator (4 °C)

 

 

Product Description:

Novel KRASG12C inhibitor, decreasing the active form of KRASG12C (KRASG12C-GTP) and pErk levels, suppressing NCI-H358 tumor growth with a TGI of 47%, exhibiting higher antiproliferative activity (IC50 = 0.66 μM) than ARS-1620 (1.32 μM)

 

Ref: https://www.sciencedirect.com/science/article/abs/pii/S0968089622003558


Analytical data click for PDF file

 

 

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