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CAS: N/A
Chemical Name: (4-(6-Chloro-7-(5-chloro-2-methoxyphenyl)-8-fluoroquinazolin-4-yl)piperazin-1-yl)(5-nitrofuran-2-yl)methanone
Purity: >98% (HPLC)
Novel KRASG12C inhibitor, decreasing the active form of KRASG12C (KRASG12C-GTP) and pErk levels, suppressing NCI-H358 tumor growth with a TGI of 47%, exhibiting higher antiproliferative activity (IC50 = 0.66 μM) than ARS-1620 (1.32 μM)
Ref: https://www.sciencedirect.com/science/article/abs/pii/S0968089622003558
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