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Glixx Laboratorie
CAS: 1934259-00-3
Chemical Name: N-[5-[[5-Chloro-4-(naphthalen-2-ylamino)pyrimidin-2-yl]amino]-2-[2-(dimethylamino)ethyl-methylamino]-4-methoxyphenyl]prop-2-enamide
Purity: >98% (HPLC)
Novel irreversible mutant-selective inhibitor of the epidermal growth factor receptor (EGFR), tageting the sensitive EGFR mutations (L858R mutation and deletion of exon 19) and resistance mutation (T790M) caused by the first generation TKIs
References:
https://pubmed.ncbi.nlm.nih.gov/?term=ASK120067+&sort=date
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