Glixx Laboratories Inc
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Glixx Laboratorie
CAS: N/A
Chemical Name: N-(4-((4-(1-Isopropyl-1H-pyrazol-4-yl)-5-methylpyrimidin-2-yl)amino)benzyl)ethenesulfonamide
For Lab R&D Uses Only
Purity: >98% (HPLC)
Novel potent and selective JAK2 kinase inhibitor with an IC50 value of 5 nM, inhibiting the phosphorylation of JAK2 and its downstream signaling pathway, exhibiting 38.6-, 54.6-, and 41.2-fold selectivity for JAK1, JAK3, and TYK2, respectively
Reference:
https://pubs.acs.org/doi/10.1021/acsmedchemlett.3c00251
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