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JAK2 inhibitor A8

 

CAS: N/A

 

Chemical Name: N-(4-((4-(1-Isopropyl-1H-pyrazol-4-yl)-5-methylpyrimidin-2-yl)amino)benzyl)ethenesulfonamide

 

 
GLXC-27660For Lab R&D Uses Only
        Cat No: GLXC-27660

 

Purity:               >98% (HPLC)

Storage:             Refrigerator (4 °C)

 

 

Product Description:

Novel potent and selective JAK2 kinase inhibitor with an IC50 value of 5 nM, inhibiting the phosphorylation of JAK2 and its downstream signaling pathway, exhibiting 38.6-, 54.6-, and 41.2-fold selectivity for JAK1, JAK3, and TYK2, respectively

 

Reference:

https://pubs.acs.org/doi/10.1021/acsmedchemlett.3c00251


Analytical data click for PDF file

 

 

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