Glixx Laboratories Inc
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Glixx Laboratorie
CAS: N/A
Chemical Name: CID613034; (Z)-N-(3,4-dichlorophenyl)-2-((3,4-dimethylphenyl)imino)-5-methylthiazolidine-3-carboxamide
Purity: >98% (HPLC)
Novel potent inhibitor of mTORC2 kinase activity, specifically inhibiting phosphorylation of mTORC2 substrates, including AKT (Ser-473), NDRG1 (Thr-346) and PKCa (Ser-657), while having no appreciable effects on the phosphorylation status of the mTORC1 substrate S6K (Thr-389) or mTORC1-dependent negative feedback loops
References:
1) https://journals.plos.org/plosone/article?id=10.1371/journal.pone.0212160
2) https://journals.plos.org/plosone/article?id=10.1371/journal.pone.0176599
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