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CAS: 2259624-71-8
Chemical Name: 1-(2-Chloro-6-fluorobenzyl)-3,3-dimethyl-2-oxo-N-(2,4,6-trifluorobenzyl)indoline-6-carboxamide
Purity: >98% (HPLC)
Novel STING agonist, binding to a cryptic pocket in the STING transmembrane domain, between the two subunits of the STING dimer, promoting the oligomerization and activation of human STING through a mechanism orthogonal to that of cGAMP
Ref: https://www.nature.com/articles/s41586-022-04559-7
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