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Glixx Laboratorie
CAS: N/A
Chemical Name: 5-(N-Benzyl-N-methylsulfamoyl)-4-chloro-2-((furan-2-ylmethyl)amino)benzoic acid
Purity: >98% (HPLC)
Novel inhibitor of lipopolysaccharide (LPS)-induced tumor necrosis factor (TNF)-α and interleukin (IL)-6 on microglia, exhibiting anti-inflammatory activity through ER-stress-mediated autophagy, significantly inducing the conversion ratio of LC3 II/I and inhibiting LPS-upregulated p-mTOR, thereby restoring impaired autophagy to modulate inflammation
Ref: https://pubs.acs.org/doi/10.1021/acschemneuro.1c00818
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