Glixx Laboratories Inc
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Glixx Laboratorie
CAS: 2230077-10-6
Chemical Name: 2-(4-(4-((5-Chloro-4-((2-(isopropylsulfonyl)phenyl)amino)pyrimidin-2-yl)amino)-5-isopropoxy-2-methylphenyl)piperidin-1-yl)-N-(17-((2-(2,6-dioxopiperidin-3-yl)-1,3-dioxoisoindolin-4-yl)amino)-3,6,9,12,15-pentaoxaheptadecyl)acetamide
Purity: >98% (HPLC)
Novel PROTAC degrader of ALK, potently decreasing cellular levels of oncogenic active ALK fusion proteins in SU-DHL-1 lymphoma and NCI-H2228 lung cancer cells
Ref: https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5924614/
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