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Glixx Laboratorie
CAS: 2364-23-0
Chemical Name: Poriferasta-5,25-dien-3beta-ol; 5,25-Stigmastadienol; NSC144945; (3S,8S,9S,10R,13R,14S,17R)-17-[(2R,5S)-5-Ethyl-6-methylhept-6-en-2-yl]-10,13-dimethyl-2,3,4,7,8,9,11,12,14,15,16,17-dodecahydro-1H-cyclopenta[a]phenanthren-3-ol
For Lab R&D Uses Only
Purity: >98% (HPLC)
Natural inhibitor of Pgp activity, decreasing cisplatin uptake in BRL cells mainly through increasing Mrp2 gene expression, also decreasing the uptake of colchicine in HEK 293 cells by increasing both Pgp and Mrp1 activity
References:
https://pubmed.ncbi.nlm.nih.gov/?term=Clerosterol+&sort=date
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