Glixx Laboratories Inc
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Glixx Laboratorie
CAS: N/A
Chemical Name: 3-((4-Methylpiperazin-1-yl)(pyridin-2-yl)methyl)-2-phenyl-1H-indol-1-ol
For Lab R&D Uses Only
Purity: >98% (HPLC)
Novel Bax activator, having greatest effect enhancing the pro-apoptotic activity of Bax with EC50 values of ∼0.1 μM and ∼0.9 μM, respectively, inducing cell death by a Bax/Bak-dependent mechanism
References:
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4847155/
https://dash.harvard.edu/bitstream/1/42015988/1/PRITZ-DISSERTATION-2018.pdf
https://www.sciencedirect.com/science/article/pii/S2211124720302254
https://pubs.acs.org/doi/pdf/10.1021/acs.jmedchem.0c02200
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