Glixx Laboratories Inc
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Glixx Laboratorie
CAS: N/A
Chemical Name: 6-Acetyl-8-cyclopentyl-2-((4-(4-ethylpiperazin-1-yl)phenyl)amino)pteridin-7(8H)-one
For Lab R&D Uses Only
Purity: >98% (HPLC)
Novel potent and selective CDK4/6 inhibitor, exhibiting significant inhibitory activity against CDK4 and CDK6 with IC50 values of 16.7 nM and 30.5 nM respectively and showing excellent selectivity to CDK1/2/7/9, displaying potent antiproliferative activities at low digital micromolar range via inducing apoptosis in breast and colon cancer cells
Ref: https://www.sciencedirect.com/science/article/abs/pii/S0960894X2200467X
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