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CDK4/6 inhibitor L12

 

CAS: N/A

 

Chemical Name: 6-Acetyl-8-cyclopentyl-2-((4-(4-ethylpiperazin-1-yl)phenyl)amino)pteridin-7(8H)-one

 

 
GLXC-26398For Lab R&D Uses Only
        Cat No: GLXC-26398

 

Purity:               >98% (HPLC)

Storage:             Refrigerator (4 °C)

 

 

Product Description:

Novel potent and selective CDK4/6 inhibitor, exhibiting significant inhibitory activity against CDK4 and CDK6 with IC50 values of 16.7 nM and 30.5 nM respectively and showing excellent selectivity to CDK1/2/7/9, displaying potent antiproliferative activities at low digital micromolar range via inducing apoptosis in breast and colon cancer cells

 

Ref: https://www.sciencedirect.com/science/article/abs/pii/S0960894X2200467X

 

Analytical data click for PDF file

 

 

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