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Glixx Laboratorie
CAS: 2857937-59-6
Chemical Name: 2-Fluoro-1-((3R,4R)-3-(pyrimidin-2-ylamino)-4-((4-(trifluoromethyl)benzyl)oxy)pyrrolidin-1-yl)prop-2-en-1-one
Purity: >98% (HPLC)
Novel, selective, and cysteine-covalent TEAD inhibitor, significantly inhibiting TEAD-regulated gene expression and proliferation of the cell lines with TEAD dependence including those derived from mesothelioma and liposarcoma
Reference:
https://pubs.acs.org/doi/10.1021/acs.jmedchem.2c01548
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