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CAS: N/A
Chemical Name: 2-Cyano-N-(4-cyano-3-methylphenyl)-3-cyclopropyl-3-hydroxyprop-2-enethioamide
Purity: >98% (HPLC)
Novel positive allosteric modulator of the GABAA receptor, not penetrating the blood brain barrier, protecting human hepatocytes against lipotoxicity-induced injury, reducing STAT3 and NF-κB phosphorylation, cleaved PARP-1 expression, and upregulating the ER chaperone PDI.
References:
https://www.frontiersin.org/articles/10.3389/fphys.2023.1106075/full
https://dom-pubs.onlinelibrary.wiley.com/doi/10.1111/dom.14719
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