Glixx Laboratories Inc

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Glixx Laboratorie

 

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GSK3685032

 

CAS: 2170137-61-6

 

Chemical Name: 2-((6-(4-Aminopiperidin-1-yl)-3,5-dicyano-4-ethylpyridin-2-yl)thio)-2-phenylacetamide

 

 
GLXC-24682For Lab R&D Uses Only
        Cat No: GLXC-24682

 

Purity:               >98% (HPLC)

Storage:             Refrigerator (4 °C)

 

 

Product Description:

First-in-class potent, non-nucleoside, reversible, DNMT1-selective inhibitor (IC50: 0.17 µM), exerting robust DNA hypomethylation and gene activation, potently inhibiting growth of cancer cell lines, displaying improved tolerability and greater DNA hypomethylation than decitabine (DAC), translating into superior antitumour activity in models of AML.

 

References:

https://pubmed.ncbi.nlm.nih.gov/?term=GSK3685032+&sort=date

 

Analytical data click for PDF file

 

 

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