Glixx Laboratories Inc
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Glixx Laboratorie
CAS: N/A2412569-41-4
Chemical Name: N-(3-((6-((1-(2-Methoxyethyl)-1H-pyrazol-4-yl)amino)-1H-pyrazolo[3,4-d]pyrimidin-1-yl)methyl)phenyl)acrylamide
Purity: >98% (HPLC)
Novel highly JAK3-selective inhibitor, showing a potent inhibition of JAK3 with an IC50 of 0.1 nM and exhibiting a 4500-fold selectivity for JAK3 than other JAK subtypes, suppressing γc cytokine–related JAK-STAT signal
Ref: https://www.science.org/doi/10.1126/sciadv.abo4363
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